Category: Bio Banking

diva

DIVA

Automated system for identifying, filling and sealing CBS™ High Security Straws

Description / Use

Starting from a batch of up to 96 primary sample tubes, DIVA automatically performs the functions of aliquoting each tube into CBS™ High Security 0.5 mL straws of different color according to the user protocol, sealing the straws, and printing and validating the aliquot identification (barcode GS1 128 and/or alphanumerical ID) on every straw.

A sorting system separates the straws according to the different colored compartments (visotubes) in which they will be stored inside the Daisy goblets.

DIVA proactively manages the consumables needed for a given production cycle. A production cycle with 2 straws per primary sample tube for instance allows an autonomy of 1h 08min without operator intervention. Refilling of consumables can be done “on the run”, without interrupting the cycle, allowing for 100% continuous workflow operation. The operator is informed in real time of the cycle progression (including estimated time left to completion), as well as the level of consumables left on the machine and when to replenish consumables and/or primary tubes.

DIVA is a fully automated platform for packaging specimens into straws. As such, it features:

  • An embedded computer running the pilot software to manage all the cycle functions and security features.
  • A touch screen used for the user interface to define the protocols and input information.

The system offers the possibility to print out protocols and production reports. Through various communication ports, DIVA offers connectivity within a network and data exchange with any Laboratory Inventory Management System (LIMS).

The flexibility of the pilot software allows to manage several protocols, all with adequate security features in conformity with Good Laboratory Practices: information such identification of protocol author and user, etc., are systematically recorded and attached to final production reports.

Positive identification of the straws can be achieved in different formats: barcode GS1 128 and/or alphanumerical code. At minima, the straw ID can be the replica of the primary sample tube ID.

Full traceability between “mother” primary tubes and “daughter” straw aliquots is ensured through an automated bar code scanning input module that read the bar codes of all primary sample tubes on the rack and an automated bar code scanning output module that validates the bar code printed on the straws.

The throughput of the system (# straws/minute) is directly linked to the aliquoting protocol (# aliquots/primary tube).

Note : DIVA can advantageously be extended with the Straw IT storage management software.

Technical Specifications

Standard starting time, maintenance and shut-down: 15 minutes a day.
All parts potentially contaminated can be easily cleaned with alcohol or a liquid non-corrosive decontaminant.

DIVA System

  • L x W x H: 1208 x 660 x 1600 mm
  • Weight: 100 kg without printer (220 lb)
  • Electrical consumption: 400 W
  • Power Supply: 110 or 220 V / 60 or 50 Hz
  • Range of working temperatures: +15℃ to +32℃ (+59℉ to +90℉)
  • Maximum elevation: 2,000 m
  • Relative humidity: 80% at +32℃ (+90℉)
Reference Description
020984 DIVA, automatic aliquoting, identification, filling and sealing of CBS™ High Security straws – with Domino printer 230 V / 50 Hz – CE
020983 DIVA, automatic aliquoting, identification, filling and sealing of CBS™ High Security straws – without printer 230 V / 50 Hz – CE

digitcool controlled

Digitcool Controlled Rate Freezers

Description

Controlled-rate freezing of all biological products (eg. plasma, all blood cells, human tissues, gametes). The stainless steel Digitcool freezer is fully programmable and easy to disinfect.

    Advantages

  • Temperature range: -150℃ to +50℃ (-238℉ to +122℉) (-180℃ reachable depending on the total sample volume)
  • Cooling rate: 0.1 to 60℃/min
  • Automatic reheating, drying and return to room temperature at end of cycle
  • Hot/cold regulator programmer (4 programs of 8 segments and 8 ramps in memory)
  • Temperature measured by PT 100 ohm probes (chamber and product)
  • Digital temperature display (chamber, product, program)
  • Can be connected to a computer terminal and a printer
  • Regulation based on “chamber” temperature
  • Liquid nitrogen dispensed through a self pressurized reservoir with 120 or 220 liters capacity

    Accessories

  • Freezing racks for 0.25 or 0.5 mL straws
  • Distribution blocks for 0.25 or 0.5 mL straws
  • Software
  • Filter unit
  • 120 L self pressurized tank
  Digitcool Mini-Digitcool Micro-Digitcool Nano-Digitcool
Outside dimensions 46×31.5×39.4″ 30.3×20.1×28.7″ 23.6x15x20.5″ 28.4×18.7×18.5″
Weight 130 kg (287 lb) 58 kg (128 lb) 38 kg (84 lb) 55 kg (121 lb)
Chamber inside dimensions 37.8×18.5×12.6″ 25.2×12.6×16.5″ 19.3×12.8×9″ 9.4x7x7.8″
Chamber volume 150 L 90 L 26 L 11.5 L
Sample capacity 3,000 CBS straws 1,392 CBS straws 240 CBS straws 33 CBS straws
Power (Heater) 2500W 2000W 1000W 1200W
Voltage / Frequency 220V/50Hz/16A 220V/50Hz/10A 220V/50Hz/6A 220V/50Hz/6A

cbs heigh security co straw

CBS High Security Co-X Straw

Fully colored CBS High Security 0.3 and 0.5 mL Straws for storage in -80℃

Description/Use

Material and dimensions identical to the CBS™ straw with an outer PETG envelope for color guiding and space saving.

New technology of plastic cover on the CBS™ base layer (ionomeric resin) which enables a longer window for printing identification.

8 different colors
Volumes available: 0.3 and 0.5 mL

CBS™ High Security Straws are designed for cryopreservation of any biological fluids such as plasma, serum, buffy coat, red blood cells, extracted DNA, urine, cell suspensions, bacterial or viral strains, gametes, embryos and gonadic tissue.

Reference Description Packaging
024314 CBS™ High Security Co-X Straw 0.3 mL – White Box of 400 Straws
024315 CBS™ High Security Co-X Straw 0.3 mL – Grey Box of 400 Straws
024316 CBS™ High Security Co-X Straw 0.3 mL – Blue Box of 400 Straws
024317 CBS™ High Security Co-X Straw 0.3 mL – Green Box of 400 Straws
024318 CBS™ High Security Co-X Straw 0.3 mL – Yellow Box of 400 Straws
024319 CBS™ High Security Co-X Straw 0.3 mL – Orange Box of 400 Straws
024320 CBS™ High Security Co-X Straw 0.3 mL – Red Box of 400 Straws
024321 CBS™ High Security Co-X Straw 0.3 mL – Pink Box of 400 Straws
Reference Description Packaging
023461 CBS™ High Security Co-X Straw 0.5 mL – White Box of 400 Straws
023462 CBS™ High Security Co-X Straw 0.5 mL – Grey Box of 400 Straws
023463 CBS™ High Security Co-X Straw 0.5 mL – Blue Box of 400 Straws
023464 CBS™ High Security Co-X Straw 0.5 mL – Green Box of 400 Straws
023465 CBS™ High Security Co-X Straw 0.5 mL – Yellow Box of 400 Straws
023466 CBS™ High Security Co-X Straw 0.5 mL – Orange Box of 400 Straws
023467 CBS™ High Security Co-X Straw 0.5 mL – Red Box of 400 Straws
023468 CBS™ High Security Co-X Straw 0.5 mL – Pink Box of 400 Straws

cbs heigh security straws

CBS High Security Straws

Material

All Cryo Bio System Straws are made from an ionomeric resin that is chemically inert, biocompatible and has physical characteristics resistant to ultra-low temperatures and pressures created by expanding liquids and liquid nitrogen. Sealed Straws are resistance tested to 150 kg/cm2 (2133 lb/sq.inch). In order to have the lot number approved, both the seals and the material should resist to pressure tests.

Plugs

Straws are filled by aspiration through an air permeable plug inside the straw.

Factory plug is made of two specifically woven polyamide fibers enclosing a polymerizing powder. In the filling procedure the powder polymerizes as soon as the liquid sample comes in contact and blocks the filling. Plugs can come in 6 different colors, for easy identification in the cold environment of a freezer.

Seal

Directly after filling, both ends of the CBS High Security Straw are thermally sealed with one of our specific machines: SYMS, PACE or MAPI. This makes the straw absolutely leak-proof, preventing contamination of the sample and its environment.

Tamper-Proof Identification

The primary identification of the straw in the cold environment of the freezer is by its color, while its definitive identification is by its alpha-numerical and bar code. The CBS High Security Straw is identified by tamper-proof ink-jet print on a jacket around the straw. The special ink is resistant to liquid nitrogen and to ice crystals. Once the straw is sealed, the jacket cannot be removed from the straw unless its ends are cut opened A second process of identification is available for 0.3 ml straws where a colored identification rod with a label can be inserted inside the straw in the compartment behind the plug. This label can only be taken from the sample when the straw is opened.

Storage

For storage, CBS High Security Straws are placed in colored compartments (visotubes) which are available in many colors. These are further placed into colored goblets. Color coding facilitates identification of straws upon retrieval. A goblet can easily hold 144 straws (12 visotubes).

Applications

Virtually any liquid sample can be stored in CBS High Security Straws. Applications include plasma, serum, buffy coat, red blood cells, extracted DNA, urine, mouth wash, cell suspensions, bacterial or viral strains, gametes and embryos.

Dimensions.

  • Storage: 0.3 ml and 0.5 ml straws.
  • Length: 130 mm after sealing.
  • Internal diameter: 2.5 mm.
Reference Description Packaging
010287 CBS High Security straw 0.3 mL with white cotton plug 20
010288 CBS High Security straw 0.3 mL with white cotton plug 100
017797 to 017802 CBS High Security straw 0.3 mL with white jacket and red, white, yellow, blue, green or purple fixed rod 75
014651 CBS High Security Straw 0.3 mL with white cotton plug 20
014650 CBS High Security Straw 0.5 mL with white cotton plug 100
016584 CBS High Security Straw 0.5 mL with red cotton plug 100
016611 to 016615 CBS High Security Straw 0.5 mL with yellow, green, blue, orange or grey cotton plug 100
024856 Sterile filling nozzles for CBS HS Straw 100
019021 to 019026 Bag of weighted identification rods 30 mm yellow, green, blue, orange, white or red 10
010272 to 010277 Identification jacket red, white, orange, green, blue or yellow 50
014939 Identification jacket clear 50
014175 Set of 2 indelible black markers 4
016730 Sterile connection tubing for syringe (individually packaged) 1
016731 Sterile connection tubing for syringe (packaged by 5) 5
010284 Sterile emptying device 20

syms

SYSM

Manual sealer for CBS™ High Security Straws and vitrifcation straws

Reference Description Packaging
016399 SYMS sealer 1
009848 Spare kit for SYMS sealer 1

Cryo Bio System has developed a thermal pulse sealing device for impermeable sealing of CBS™ High Security straws in ionomeric resin. The sealing device is electronically operated by a push-button or foot pedal as desired.

Technical Specifications

Setup, maintenance and downtime time are approximately 5 minutes per day.
Potentially contaminated parts of the system can be cleaned with ethanol or non-corrosive decontamination fluids.

Dimensions (L x W x H) : 230 x 220 x 170 mm
Weight: 6 kg (13 lb)
Electrical requirements: 220V/50 Hz or 110V/60 Hz

syms iii

SYMS III

Unique sealer for CBS High Security straws and tubes

Description / Use

The SYMS III thermally seals 0.3 mL, 0.5 mL and 2 mL CBS™ High Security straws as well as CBS™ High Security Vitrification straws and CBS™ High Security Tubes for top quality cryopreservation of biological samples.

Key Characteristics

  • A multilingual interface (French, English, Spanish and Chinese) + 4 optional languages
  • A color touch screen that can be used while wearing laboratory gloves
  • View of the machine cycles: preheating, ready status, sealing in progress, etc.
  • Specially adapted pre-programming for each CBS™ product’s sealing temperature and time
  • Two sealing methods: fully automatic detection or operator-controlled via the touch screen
  • Alarms and alert messages signal faults
  • Tracking display and maintenance modes display
  • Easy to clean and maintain

Technical Specifications

Dimensions (L x W x H) : 335 x 250 x 105 mm
Weight: 3 kg
Power Supply: 110 or 220 v / 60 or 50 Hz

Reference Description Packaging
025547 SYMS III sealer 1
026550 Sealing jaws set for SYMS III 1